The AnteAGE® Accelerator
The AnteAGE®MD Accelerator
AnteAGE® MD contains twice the Stem Cytokines™ found in AnteAGE®, along with additional ingredients to provide enhanced anti-aging, pro-healing and anti-inflammatory benefits. With daily use it improves the health and appearance of skin, no matter what one’s age, and is particularly well suited for use as a topical adjuvant to promote healing and reduce inflammation following medical esthetic procedures.
The stem cell technology behind AnteAGE® MD is cutting edge and published in multiple peer-reviewed medical journals. Combining it with more than a dozen additional scientifically proven actives makes AnteAGE MD uniquely effective and the most complete skincare system available.
Its powerful ingredients also make it the perfect post-procedure topical adjuvant following laser, microneedling, abrasive, and other ablative or collagen inducting medical esthetic treatments.
KEY ACTIVE INGREDIENTS:
Stem Cytokine™ Retinol (Vitamin A)
Isoflavones Vitamin E Acetate
Algae Extract Sodium Hyaluronate
Alpha Lipoic Acid Organic Black Tea
Vitamin C Vitamin B5
Coenzyme Q10 Grape Seed Extract
Ceramide-2 Shea Butter
Ready to take the next step?
There is a lot of amazing science and years of experience in the AnteAGE® Serum.
To learn the definition, physiology, and published literature documenting the benefit of each active Serum ingredient, click on the appropritate tab below
Retinol (Vitamin A)
Definition: Retinol is one of the animal forms of vitamin A. When converted to the retinal (retinaldehyde) form, vitamin A is essential for vision, and when converted to retinoic acid, is essential for skin health, teeth remineralization and bone growth. These chemical compounds are collectively known as retinoids.
Physiology: Retinol is a vitamin A derivatives that unclogs pores, boosts collagen and elastin production to reduce fine lines, and speeds cell turnover to even out discoloration and smooth the skin—sometimes in as little as four weeks. Vitamin A is also required in the production of rhodopsin, the visual pigment used in low light levels. Vitamin A is essential for the correct functioning of epithelial cells. In vitamin A deficiency, mucus-secreting cells are replaced by keratin producing cells, leading to xerosis. Vitamin A is essential to maintain intact epithelial tissues as a physical barrier to infection; it is also involved in maintaining a number of immune cell types from both the innate and acquired immune systems. Retinoic acid is an influential factor used in differentiation of stem cells to more committed fates, echoing retinoic acid’s importance in natural embryonic developmental pathways.
1. Improvement of naturally aged skin with vitamin A (retinol). Archives of Dermatology. May 2007
2. Improvement of naturally aged skin with vitamin A (retinol). Archives of Dermatology. May 2007
3. Topical Retinoids in the Management of Photodamaged Skin: From Theory to Evidence-based Practical Approach. The British Journal of Dermatology. June 2010
4. In vitro metabolism by human skin and fibroblasts of retinol, retinal and retinoic acid. Experimental Dermatology. May 2007
Definition: Phytoestrogens are plant‐derived molecules that structurally resemble endogenous estrogens. Phytoestrogens exhibit some estrogen agonist‐like properties but can also act as partial estrogen receptor antagonists.
Physiology: Because of their mixed agonist/antagonist estrogen receptor profile, phytoestrogens have received considerable attention as potential alternatives to estrogen. Studies have demonstrated that genistein may prevent photoageing in human skin. Other studies have reported that genistein and daidzein stimulate hyaluronic acid production in human keratinocyte culture. A recent European study had examined the effect of a cosmetic cream preparation including isoflavone (Novadiol) in 234 postmenopausal women and had showed improvement in the skin dryness and wrinkles after 12 weeks of treatment.
1. Phytoestrogens: the biochemistry, physiology, and implications for human health of soy isoflavones. American Journal of Clinical Nutrition, Dec 1988
2. Protective Effects of Dietary Soy Isoflavones against UV-Induced Skin-Aging in Hairless Mouse Model. Journal American College of Nutrition. April 2004
3. In vitro and in vivo evaluation of topical delivery and potential dermal use of soy isoflavones genistein and daidzein. International Journal of Pharmaceutics. Nov 2008
Tocopheryl Acetate (Vitamin E Acetate)
Definition: Tocopheryl acetate, also known as vitamin E acetate, is a common vitamin supplement often used in dermatological products such as skin creams.
Physiology: It is Tocopherol acetate is not oxidized and can penetrate through the skin to the living cells, where about 5% is converted to free tocopherol and provides beneficial antioxidant effects.Tocopheryl acetate is used as an alternative to tocopherol itself because the phenolic hydroxyl group is blocked, providing a less acidic product with a longer shelf life. It is believed that the acetate is slowly hydrolyzed once it is absorbed into the skin, regenerating tocopherol and providing protection against the sun’s ultraviolet rays.
1. Linus Pauling Institute Research Report: All About E
2. Hydrolysis of RRR-alpha-tocopheryl acetate (vitamin E acetate) in the skin and its UV protecting activity (an in vivo study with the rat)”. Journal of Photochemistry and Photobiology July 1995
3. Cutaneous vitamins A and E in the context of ultraviolet- or chemically-induced oxidative stress. Skin Pharmacology and Physiol.ogy Nov-Dec 2001
Tetrahexyldecyl Ascorbate (Vitamin C Ester)
Definition: Tetrahexyldecyl Ascorbate is a very stable, oil-soluble Vitamin C ester which has anti-oxidant activity, inhibiting lipid peroxidation.
Physiology: Topical use can mitigate the damaging effects of UV exposure. Studies have shown it to stimulate collagen production as well as clarifying and brightening the skin by inhibiting melanogenesis (the production of pigment) thereby promoting a more even skin tone. Unlike ascorbic acid, it will not exfoliate or irritate skin.
1. Topical vitamin C protects porcine skin from ultraviolet radiation-induced damage. British Journal of Dermatology. September 1992
2. UV photoprotection by combination topical antioxidants vitamin C and vitamin E.
Journal of the American Academy of Dermatology, June 2003
3. Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo. Experimental. Dermatology. June 2003
Panthenol (Pro-Vitamin B5)
Definition: Panthenol is the alcohol analog of pantothenic acid (vitamin B5) and is thus a provitamin of B5.
Physiology: In cosmetics, panthenol is a humectant, emollient and moisturizer. It also stimulates collagen production.
Ubiquinone (Coenzyme Q10)
Definition: Electron-carrying coenzyme found especially in mitochondria that functions in oxidative phorphorylation as an electron transporter.
Physiology: This oil-soluble, vitamin-like substance is present in most eukaryotic cells, primarily in the mitochondria. It is a component of the electron transport chain and participates in aerobic cellular respiration, generating energy in the form of ATP. The antioxidant nature of CoQ10 derives from its energy carrier function. In its reduced form, the CoQ10 molecule holds electrons rather loosely, so the CoQ10 molecule will quite easily give up one or both electrons and, thus, act as an antioxidant.
1. Biochemical rationale and experimental data on the antiaging properties of CoQ(10) at skin level. Biofactors. Sept 2011
2. Diet-derived and topically applied tocotrienols accumulate in skin and protect the tissue against ultraviolet light-induced oxidative stress. 3. Asia Pacific Journal of Clinical Nutrition .1997
Ubiquinol-10 is an effective lipid-soluble antioxidant at physiological concentrations. Proceedings of the National Academy of Science USA 1990
4. Treatment of CoQ(10) deficient fibroblasts with ubiquinone, CoQ analogs, and vitamin C: time- and compound-dependent effects. PLoS One. Jul 2010
Grape Seed Extract
Definition: Derivatives from whole grape seeds that have high concentration of vitamin E, flavenoids, linoleic acid and phenolic OPCs.
Physiology: Contains chemicals known as polyphenols having antioxidant activity. One particular type of phenol found in grape seed is called procyanidin thought to protect the body from premature ageing. Procyanidins also bond with collagen, the most abundant protein in the body and a key component of skin. The bonding promotes cell health and skin elasticity, making it seem more youthful, Procyanidins additionally help protect the body from sun damage. OPCs induced vascular endothelial growth factor and accelerated healing of injured skin in mice.
1. Dermal wound healing properties of redox-active grape seed proanthocyanidins. Free Radical Biology and Medicine. October 2002
2. Grape seed proanthocyanidines and skin cancer prevention: Inhibition of oxidative stress and protection of immune system. Molecular Nutr ition and Food Research. June 2008
Organic Black Tea
Definition: Black tea is a type of tea that is more oxidized than the oolong, green, and white teas. All four types are made from leaves of the shrub (or small tree) Camellia sinensis.
Physiology: Theaflavins: the polyphenol in black tea associated with health effects including antioxidant potency. Topical application has been associated with UVB protective effect and prevention of skin cancer.